1.1 Willett: Introduction
1.3 Pognan: Challenges and needs to use existing data in drug development_
1.4 Casey: A strategic roadmap to the implementation of alternatives
1.5 Cuthbert: Clinical Point of view: current practices, challenges and needs
1.8 Adcock: 21st century disease models of COPD
2.1 Pillai: Overview of NIH Big data projects, LINCS in particular
2.2 Colvis: Biomedical Data Translator – What’s it going to take?
2.3 Chute: Translator and Fanconi Anemia
3.1 Simeonov: Tox21 and beyond for pharma and biomed
3.2 Low: Organs on a chip: applications for testing and research
3.3 Berg: Primary Cell-Based Phenotypic Profiling for Building Human Outcome Pathways
3.4 Hughes: Systems Biology Approach to Cancer
3.5 Willett: How might a “pathway-based” approach help (e.g. AOPs)?
3.6 Sutherland: A network based approach to understanding drug toxicity and its application to human liver disease
3.7 Abernethy: Systems Pharmacology (PredicTox)